Signal layer

NeoTag™: immune signal installation.

Designed to install recognizable immune markers directly onto the tumor cell surface, so an immune-silent tumor can become a recognizable target.

Explore the platform

Borrowing recognition the immune system already has.

NeoTag™ is designed to introduce engineered immune identifiers, drawn from pathogen-derived epitopes the immune system already has durable memory for, onto tumor cells. The goal is a recognizable target without building a new immune response from scratch.

Borrows an existing immune response
Surface-level only, with no genetic change
No viral vectors
Engineered for stable presentation
Back to the platform
Recognizable by design

Built on signals the immune system already knows how to recognize.

Surface-level installation

Acts at the tumor cell surface, with no edits to the genome.

Stable presentation

Engineered for presentation at the right density and orientation.

Existing immune pathways

Designed to be read by existing T-cell and NK-cell pathways.

Combination-ready

Intended to complement current and future immunotherapies.

Modular

Designed to work with Atraxis™ delivery variants.

What to know about
NeoTag™

Where it fits

NeoTag™ is the signal layer. Atraxis™ delivers it, AegisCore™ governs when and where it acts, and StratIQ™ coordinates the system.

Current status

Provisional patent applications filed. Surface-display feasibility is a primary objective of our preclinical work.

An important note

LurexBio is a preclinical-stage company. Platform descriptions reflect design intentions and scientific hypotheses, not demonstrated results.

Signal layer · 1 of 4

How NeoTag™ works

Part of one operating system

  1. 01Invisible
  2. 02Arrival
  3. 03Installation
  4. 04Recognition
  5. 05Engagement

Step 01

Invisible

Many solid tumors display few signals the immune system can recognize. T cells pass by without engaging.

Step 02

Arrival

NeoTag markers travel to the tumor surface inside non-viral carriers.

Step 03

Installation

The markers are designed to anchor in the tumor cell membrane, presenting a recognizable signal without editing the tumor genome.

Step 04

Recognition

T cells are designed to recognize the installed marker, a signal the immune system already knows how to read.

Step 05

Engagement

Recognition is intended to draw more immune cells to the tumor, so a target that was hidden becomes visible.

Illustrations are conceptual.

Explore the other layers

Vesicle-mediated membrane fusion designed to deliver the signal to the tumor surface.

Programmable safety and activation logic that governs when, where, and how the platform acts.

The governing decision framework that coordinates every layer as one system.